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Description
Dosage forms of drug contain various excipients along with Active Pharmaceutical Ingredient (API) to make a complete dosage form and assist in manufacturing process. Advancement in drug delivery technology led to use of these excipients in novel dosage form to fulfil the criteria of specific functions like extent and/or rate of drug release and absorption. As plant polysaccharides comply with many requirements of pharmaceutical excipients such as non-toxicity, stability, availability, and renewability, they are extensively investigated for use in the development of solid oral dosage form. Furthermore, polysaccharides with varying physicochemical properties can be extracted from plants at relatively low cost and chemically modified to suit specific needs. Many plant polysaccharides are successfully used as viscosity enhancer, disintegrating agent, etc. in modified release dosage forms. Some plant polysaccharides have even shown environmental-responsive characteristics with the potential to control drug release at the target site according to specific therapeutic needs. This study discusses some of the most important plant-derived polymeric compounds that are used or investigated as excipients in drug delivery systems.