Speaker
Description
In the last decade, various research work and review articles are being reported showing the importance of niosomes and their advantages over the other vesicular formulations. Niosomes are vesicular structure that is made up of non-ionic surfactant, cholesterol, and sometimes charged inducers. The non-ionic surfactants assemble among themselves to form the bilayer vesicular structure. The vesicular structure so formed is used to modify the distribution profile of the drugs and thus helps in forming a sustained release formulation. The unique structure formed helps to encapsulate hydrophilic drugs, hydrophobic drugs as well as amphiphilic drugs within the niosomal vesicular structure. Niosomes are bio-degradable, bio-compatible, and non-immunogenic in nature. They are more stable, economic, and less toxic compared to that liposomes. The niosomes could be prepared by using various methods such as thin film hydration method, ether injection method, modified ether injection method, sonication method, etc. Different niosomal preparations are already prepared which has targeted different diseases that have proved to enhance the therapeutic properties by various folds as compared to the available marketed products.