16–18 Dec 2022
Birla Institute of Technology, Mesra
Asia/Kolkata timezone

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An Invivo approach to investigate the wound healing activity of Sericin on animal model.

Not scheduled
10m
Birla Institute of Technology, Mesra

Birla Institute of Technology, Mesra

Department of Pharmaceutical Sciences & Technology
Poster Pharmaceutical Sciences & Technology Poster Presentation

Speaker

Mr Ravi Pratap Singh (BIT, Mesra)

Description

A number of advancements have been made in wound healing science. Over the past few years, there has been an increase in the topic of wound healing which has gained more attention in recent years. Underlying immunological disease complications such as diabetes mellitus can lead to fatal presentations. Currently, there are very few medications and formulations available for wound healing activity, and many of them are associated with severe side effects, including cancer and other skin diseases. Therefore, in the modern era, there has been an increase in research aimed at developing new wound-healing products. A series of in vitro and in vivo studies were conducted using TASAR’s Sericin extracted from cocoons to test its wound healing properties. Hence, it was used for in vivo experiments such as analgesic tests, hydroxyproline quantification, cotton pellet tests and so on to determine the potency of Sericin towards wound healing activity. When Sericin protein was mixed with gel in a fixed proportion, significant changes in tensile strength were observed when compared to normal and standard gel formulations.
Sericin's potency for wound healing activity was demonstrated by the application of an excision model and an incision model. For each instance, significant values were achieved at **p<0.05. Hence, this could lead to the discovery of new avenues of research in the near future as a result of Sericin.

Primary author

Mr Ravi Pratap Singh (BIT, Mesra)

Co-author

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