The COVID-19 pandemic has set back progress made on antimicrobial resistance (AMR). Without urgent re-focus, we risk slowing down drug discovery and providing treatment for drug resistant Mycobacterium tuberculosis. It is vital to develop new antibiotics with novel mechanism(s) of action to combat different physiological states of TB-causing bacilli. The bacterial cell-wall is a proven...
Interaction of Prof. Sanjib Bhakta with Graduate and Doctoral research scholars.
Tuberculosis (TB), a contagious infection caused by Mycobacterium tuberculosis, poses a severe risk to public health. This airborne infection is becoming more complex in the upcoming days. Therefore, controlling such multi-drug resistant TB (MDR-TB) and extensively drug-resistant TB (XDR-TB) has become difficult. The MDR-TB is developed when the strain become resistant to isoniazid and...
OBJECTIVE - The present study is to design, synthesize and molecular docking of triazolothiadiazole derivatives as potential anticancer agents.
METHOD – Eleven new derivatives of imidazopyridine linked triazolothiadiazole were synthesized in three steps, and their chemical structures of the title compounds (9a-k) were proved by IR, 1H NMR, 13C NMR, Mass spectroscopic and elemental analyses....
Rasmita Jena1, 2, Durga Madhab Kar2
1 School of Pharmacy and Life Sciences, Centurion University of Technology and Management, Bhubaneswar, Odisha, 752050
2 Department of Pharmacology, School of Pharmaceutical Sciences
Siksha ‘O’ Anusandhan Deemed to be University, Kalinga Nagar, Bhubaneswar, Odisha, 751003
Background: Aporosa octandra (Euphorbiaceae) is an ethnomedicinal evergreen...
Antimicrobial resistance is one of the emerging global “silent threats”, increasing the burden on healthcare and the economy. The mortality rate will increase up to 10 million per year by 2050. Thus it becomes vital for the early detection and prevention of AMR. The reliance on Artificial Intelligence (AI) and Machine Learning (ML) is increasing due to their higher data acquisition and...